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pentobarbital will minimize the level or influence of atogepant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Encouraged atogepant dosage with concomitant use of potent or average CYP3A4 inducers is thirty mg or 60 mg qDay.pentobarbital will lower the level or effect of oliceridine by affecting hepatic/int